Title | Costs of the metabolic syndrome in elderly individuals: findings from the Cardiovascular Health Study. |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Curtis, LH, Hammill, BG, M Bethel, A, Anstrom, KJ, Gottdiener, JS, Schulman, KA |
Journal | Diabetes Care |
Volume | 30 |
Issue | 10 |
Pagination | 2553-8 |
Date Published | 2007 Oct |
ISSN | 1935-5548 |
Keywords | Aged, Aged, 80 and over, Cholesterol, HDL, Continental Population Groups, Cost of Illness, Diabetic Angiopathies, Female, Humans, Hypertension, Interviews as Topic, Male, Medicare, Metabolic Syndrome, Multivariate Analysis, Obesity, Patient Education as Topic, Prospective Studies, Regression Analysis, United States |
Abstract | <p><b>OBJECTIVE: </b>The cardiovascular consequences of the metabolic syndrome and its component risk factors have been documented in elderly individuals. Little is known about how the metabolic syndrome and its individual components translate into long-term medical costs.</p><p><b>RESEARCH DESIGN AND METHODS: </b>We used log-linear regression models to assess the independent contributions of the metabolic syndrome and its individual components to 10-year medical costs among 3,789 individuals aged > or = 65 years in the Cardiovascular Health Study.</p><p><b>RESULTS: </b>As defined by the National Cholesterol Education Program Third Adult Treatment Panel report, the metabolic syndrome was present in 47% of the sample. Total costs to Medicare were 20% higher among participants with the metabolic syndrome ($40,873 vs. $33,010; P < 0.001). Controlling for age, sex, race/ethnicity, and other covariates, we found that abdominal obesity, low HDL cholesterol, and elevated blood pressure were associated with 15% (95% CI 4.3-26.7), 16% (1.7-31.8), and 20% (10.1-31.7) higher costs, respectively. When added to the model, the metabolic syndrome composite variable did not contribute significantly (P = 0.32).</p><p><b>CONCLUSIONS: </b>Abdominal obesity, low HDL cholesterol, and hypertension but not the metabolic syndrome per se are important predictors of long-term costs in the Medicare population.</p> |
DOI | 10.2337/dc07-0460 |
Alternate Journal | Diabetes Care |
PubMed ID | 17623825 |
Grant List | N01HC15103 / HC / NHLBI NIH HHS / United States N01HC35129 / HC / NHLBI NIH HHS / United States N01HC45133 / HC / NHLBI NIH HHS / United States N01HC55222 / HC / NHLBI NIH HHS / United States N01HC75150 / HC / NHLBI NIH HHS / United States N01HC85079 / HC / NHLBI NIH HHS / United States N01HC85080 / HC / NHLBI NIH HHS / United States N01HC85081 / HC / NHLBI NIH HHS / United States N01HC85082 / HC / NHLBI NIH HHS / United States N01HC85083 / HC / NHLBI NIH HHS / United States N01HC85084 / HC / NHLBI NIH HHS / United States N01HC85085 / HC / NHLBI NIH HHS / United States N01HC85086 / HC / NHLBI NIH HHS / United States U01HL080295 / HL / NHLBI NIH HHS / United States |