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Physical activity and white matter lesion progression: assessment using MRI.
Tuesday,2012-11-06 12:08 America/Los_Angeles — eenright
| Title | Physical activity and white matter lesion progression: assessment using MRI. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Podewils, LJ, Guallar, E, Beauchamp, N, Lyketsos, CG, Kuller, LH, Scheltens, P |
| Journal | Neurology |
| Volume | 68 |
| Issue | 15 |
| Pagination | 1223-6 |
| Date Published | 2007 Apr 10 |
| ISSN | 1526-632X |
| Keywords | Activities of Daily Living, Aged, Alzheimer Disease, Cognition Disorders, Cohort Studies, Demyelinating Diseases, Disease Progression, Female, Humans, Magnetic Resonance Imaging, Male, Motor Activity, United States |
| Abstract | <p>We evaluated the association between physical activity and changes in white matter lesions (WMLs) on MRI in a sample of 179 older adults comprising 59 incident cases of Alzheimer disease, 60 persons with mild cognitive impairment, and 60 persons who remained cognitively stable over a median 5-year follow-up. Physical activity was not significantly associated with a decreased rate of periventricular or deep WML progression.</p> |
| DOI | 10.1212/01.wnl.0000259063.50219.3e |
| Alternate Journal | Neurology |
| PubMed ID | 17420407 |
| Grant List | AG15928 / AG / NIA NIH HHS / United States N01-HC 85086 / HC / NHLBI NIH HHS / United States N01-HC-15103 / HC / NHLBI NIH HHS / United States N01-HC-35129 / HC / NHLBI NIH HHS / United States N01-HC-85079 / HC / NHLBI NIH HHS / United States |