Title | {Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Spracklen, CN, Karaderi, T, Yaghootkar, H, Schurmann, C, Fine, RS, Kutalik, Z, Preuss, MH, Lu, Y, Wittemans, LBL, Adair, LS, Allison, M, Amin, N, Auer, PL, Bartz, TM, her, M, Boehnke, M, Borja, JB, Bork-Jensen, J, Broer, L, Chasman, DI, Chen, YI, Chirstofidou, P, Demirkan, A, van Duijn, CM, Feitosa, MF, Garcia, ME, Graff, M, Grallert, H, Grarup, N, Guo, X, Haesser, J, Hansen, T, Harris, TB, Highland, HM, Hong, J, Ikram, MA, Ingelsson, E, Jackson, R, Jousilahti, P, nen, M, Kizer, JR, Kovacs, P, Kriebel, J, Laakso, M, Lange, LA, ki, T, Li, J, Li-Gao, R, Lind, L, Luan, J, inen, LP, MacGregor, S, Mackey, DA, Mahajan, A, Mangino, M, ö, S, McCarthy, MI, McKnight, B, Medina-Gomez, C, Meigs, JB, Molnos, S, Mook-Kanamori, D, Morris, AP, de Mutsert, R, Nalls, MA, Nedeljkovic, I, North, KE, Pennell, CE, Pradhan, AD, Province, MA, Raitakari, OT, Raulerson, CK, Reiner, AP, Ridker, PM, Ripatti, S, Roberston, N, Rotter, JI, Salomaa, V, rate, AA, Sitlani, CM, Spector, TD, Strauch, K, Stumvoll, M, Taylor, KD, Thuesen, B, njes, A, Uitterlinden, AG, Venturini, C, Walker, M, Wang, CA, Wang, S, Wareham, NJ, Willems, SM, K. van Dijk, W, Wilson, JG, Wu, Y, Yao, J, Young, KL, Langenberg, C, Frayling, TM, inen, TO, Lindgren, CM, Loos, RJF, Mohlke, KL |
Journal | Am J Hum Genet |
Volume | 105 |
Pagination | 15–28 |
Date Published | Jul |
Abstract | ) with at least one obesity or lipid trait. Candidate genes include PRKAR2A, PTH1R, and HDAC9, which have been suggested to play roles in adipocyte differentiation or bone marrow adipose tissue. Taken together, these findings provide further insights into the processes that influence circulating adiponectin levels. |