Title | {Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Portilla-Fernandez, E, Klarin, D, Hwang, SJ, Biggs, ML, Bis, JC, Weiss, S, Rospleszcz, S, Natarajan, P, Hoffmann, U, Rogers, IS, Truong, QA, lker, U, rr, M, low, R, Criqui, MH, Allison, M, Ganesh, SK, Yao, J, Waldenberger, M, Bamberg, F, Rice, KM, Essers, J, Kapteijn, DMC, van der Laan, SW, de Knegt, RJ, Ghanbari, M, Felix, JF, Ikram, MA, Kavousi, M, Uitterlinden, AG, Roks, AJM, Danser, AHJ, Tsao, PS, Damrauer, SM, Guo, X, Rotter, JI, Psaty, BM, Kathiresan, S, lzke, H, Peters, A, Johnson, C, Strauch, K, Meitinger, T, O'Donnell, CJ, Dehghan, A |
Journal | Hum Mol Genet |
Volume | 31 |
Pagination | 3566–3579 |
Date Published | Oct |
Abstract | 0.0001), known risk factors for AAA, consistent with a causal association with AAD. Our findings point to new biology as well as highlighting gene regions in mechanisms that have previously been implicated in the genetics of other vascular diseases. |