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{Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study

Title{Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study
Publication TypeJournal Article
Year of Publication2022
AuthorsPortilla-Fernandez, E, Klarin, D, Hwang, SJ, Biggs, ML, Bis, JC, Weiss, S, Rospleszcz, S, Natarajan, P, Hoffmann, U, Rogers, IS, Truong, QA, lker, U, rr, M, low, R, Criqui, MH, Allison, M, Ganesh, SK, Yao, J, Waldenberger, M, Bamberg, F, Rice, KM, Essers, J, Kapteijn, DMC, van der Laan, SW, de Knegt, RJ, Ghanbari, M, Felix, JF, Ikram, MA, Kavousi, M, Uitterlinden, AG, Roks, AJM, Danser, AHJ, Tsao, PS, Damrauer, SM, Guo, X, Rotter, JI, Psaty, BM, Kathiresan, S, lzke, H, Peters, A, Johnson, C, Strauch, K, Meitinger, T, O'Donnell, CJ, Dehghan, A
JournalHum Mol Genet
Volume31
Pagination3566–3579
Date PublishedOct
Abstract0.0001), known risk factors for AAA, consistent with a causal association with AAD. Our findings point to new biology as well as highlighting gene regions in mechanisms that have previously been implicated in the genetics of other vascular diseases.
ePub date: 
22/10