You are here
Subclinical cardiovascular disease in older adults: insights from the Cardiovascular Health Study.
Tuesday,2012-11-06 12:06 America/Los_Angeles — eenright
| Title | Subclinical cardiovascular disease in older adults: insights from the Cardiovascular Health Study. |
| Publication Type | Journal Article |
| Year of Publication | 2004 |
| Authors | Chaves, PHM, Kuller, LH, O'Leary, DH, Manolio, TA, Newman, AB |
| Corporate/Institutional Authors | Cardiovascular Health Study, |
| Journal | Am J Geriatr Cardiol |
| Volume | 13 |
| Issue | 3 |
| Pagination | 137-51 |
| Date Published | 2004 May-Jun |
| ISSN | 1076-7460 |
| Keywords | Aged, Cardiovascular Diseases, Coronary Artery Disease, Heart Failure, Humans, Longitudinal Studies, Prevalence, Risk Assessment, Risk Factors |
| Abstract | <p>Knowledge about the epidemiology of subclinical cardiovascular disease (SCVD) in older adults may hold the key for improved opportunities for primary prevention of cardiovascular disease (CVD), a top clinical and public health priority. This review reports findings on the prevalence of SCVD and the ability of SCVD measures to predict incident and adverse outcomes from one of the largest (N=5888) and most comprehensive prospective observational studies on SCVD in older adults, the Cardiovascular Health Study. According to a composite index that combined SCVD measures from different vascular beds, the overall prevalence of SCVD was 37%, making it as common as clinically overt CVD in older adults. SCVD measures strongly predicted incident CVD, stroke, mortality, frailty, and physical and cognitive decline, even after adjustment for traditional CVD risk factors. Ongoing research will address the potential use of SCVD for clinical decision making in older adults.</p> |
| DOI | 10.1111/j.1076-7460.2004.02120.x |
| Alternate Journal | Am J Geriatr Cardiol |
| PubMed ID | 15133417 |
| Grant List | N01-HC-15103 / HC / NHLBI NIH HHS / United States N01-HC-35129 / HC / NHLBI NIH HHS / United States N01-HC-85079 / HC / NHLBI NIH HHS / United States N01-HC-85086 / HC / NHLBI NIH HHS / United States |