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The role of comorbidity in the assessment of intermittent claudication in older adults.

TitleThe role of comorbidity in the assessment of intermittent claudication in older adults.
Publication TypeJournal Article
Year of Publication2001
AuthorsNewman, AB, Naydeck, BL, Sutton-Tyrrell, K, Polak, JF, Kuller, LH
Corporate/Institutional AuthorsCardiovascular Health Study Research Group,
JournalJ Clin Epidemiol
Volume54
Issue3
Pagination294-300
Date Published2001 Mar
ISSN0895-4356
KeywordsAged, Angina Pectoris, Arterial Occlusive Diseases, Cerebrovascular Disorders, Cohort Studies, Comorbidity, Diabetes Mellitus, Female, Humans, Intermittent Claudication, Leg, Male, Prevalence, Sensitivity and Specificity, Surveys and Questionnaires
Abstract<p>The prevalence of intermittent claudication (IC) in older adults by questionnaire is less than 5% while the prevalence of peripheral arterial disease (PAD) by non-invasive testing is 2-4-fold higher. Comorbid conditions may result in under-reporting intermittent claudication (IC) as assessed by the Rose Questionnaire. We examined characteristics of those who report leg pain in relationship to other comorbid conditions and disability in 5888 participants of the Cardiovascular Health Study (CHS). Older adults with exertional leg pain, not meeting criteria for IC, had a higher prevalence of PAD on non-invasive testing with the ankle-arm index than those without pain, as well as a higher prevalence of arthritis. The pattern of responses suggested that pain for both conditions was reported together. The Rose Questionnaire for IC is specific for PAD, but a negative questionnaire does not indicate a lack of symptoms, rather the presence of PAD along with other conditions that can cause pain.</p>
DOI10.1016/s0895-4356(00)00308-5
Alternate JournalJ Clin Epidemiol
PubMed ID11223327
Grant ListN01-HC-85079 / HC / NHLBI NIH HHS / United States
N01-HC-85086 / HC / NHLBI NIH HHS / United States
RC- HL 15103 / HL / NHLBI NIH HHS / United States
RC-HL 35129 / HL / NHLBI NIH HHS / United States