You are here

Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study.

TitleCognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study.
Publication TypeJournal Article
Year of Publication2000
AuthorsSaxton, J, Ratcliff, G, Newman, A, Belle, S, Fried, L, Yee, J, Kuller, L
JournalNeuroepidemiology
Volume19
Issue6
Pagination312-9
Date Published2000 Nov-Dec
ISSN0251-5350
KeywordsAged, Cardiovascular Diseases, Cognition Disorders, Female, Humans, Hypertension, Male, Severity of Illness Index, Wechsler Scales
Abstract<p>The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels.</p>
DOI10.1159/000026270
Alternate JournalNeuroepidemiology
PubMed ID11060505
Grant ListMH 46643 / MH / NIMH NIH HHS / United States
N01-HC-85080 / HC / NHLBI NIH HHS / United States
N01-HC-95079 / HC / NHLBI NIH HHS / United States