Title | Results differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Ning, Y, McAvay, G, Chaudhry, SI, Arnold, AM, Allore, HG |
Journal | Exp Aging Res |
Volume | 39 |
Issue | 1 |
Pagination | 27-43 |
Date Published | 2013 |
ISSN | 1096-4657 |
Keywords | Activities of Daily Living, Aged, Arthritis, Cardiac Rehabilitation, Cardiovascular Diseases, Data Interpretation, Statistical, Female, Humans, Longitudinal Studies, Male, Outcome Assessment (Health Care), Regression Analysis, Social Support |
Abstract | <p><b>UNLABELLED: </b>BACKGROUND/STUDY CONTEXT: The objective of this study was to examine sequential and simultaneous approaches to multiple imputation of missing data in a longitudinal data set where losses due to death were common.</p><p><b>METHODS: </b>Comparison of results from analyses and simulations of time to incident difficulty of activities of daily living (ADL) in the Cardiovascular Health Study when missing data were imputed simultaneously or sequentially.</p><p><b>RESULTS: </b>Results differed with imputation methods. The largest proportional differences in 12 risk factor parameter estimates were heart failure by 106%, social support by 33%, and arthritis by 27%.</p><p><b>CONCLUSION: </b>Decedents' final characteristics were influential on future imputations of those with missing values.</p> |
DOI | 10.1080/0361073X.2013.741968 |
Alternate Journal | Exp Aging Res |
PubMed ID | 23316735 |
PubMed Central ID | PMC3547387 |
Grant List | N01-HC-80007 / HC / NHLBI NIH HHS / United States U01 HL080295 / HL / NHLBI NIH HHS / United States N01 HC015103 / HC / NHLBI NIH HHS / United States P30AG21342 / AG / NIA NIH HHS / United States N01HC55222 / HL / NHLBI NIH HHS / United States N01-HC-85086 / HC / NHLBI NIH HHS / United States N01HC85086 / HL / NHLBI NIH HHS / United States P30 AG021342 / AG / NIA NIH HHS / United States K23AG030986 / AG / NIA NIH HHS / United States N01 HC-55222 / HC / NHLBI NIH HHS / United States N01-HC-75150 / HC / NHLBI NIH HHS / United States N01HC75150 / HL / NHLBI NIH HHS / United States N01-HC-85079 / HC / NHLBI NIH HHS / United States K23 AG030986 / AG / NIA NIH HHS / United States N01HC85079 / HL / NHLBI NIH HHS / United States N01 HC045133 / HC / NHLBI NIH HHS / United States N01 HC035129 / HC / NHLBI NIH HHS / United States |