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Results differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data.

TitleResults differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data.
Publication TypeJournal Article
Year of Publication2013
AuthorsNing, Y, McAvay, G, Chaudhry, SI, Arnold, AM, Allore, HG
JournalExp Aging Res
Volume39
Issue1
Pagination27-43
Date Published2013
ISSN1096-4657
KeywordsActivities of Daily Living, Aged, Arthritis, Cardiac Rehabilitation, Cardiovascular Diseases, Data Interpretation, Statistical, Female, Humans, Longitudinal Studies, Male, Outcome Assessment (Health Care), Regression Analysis, Social Support
Abstract<p><b>UNLABELLED: </b>BACKGROUND/STUDY CONTEXT: The objective of this study was to examine sequential and simultaneous approaches to multiple imputation of missing data in a longitudinal data set where losses due to death were common.</p><p><b>METHODS: </b>Comparison of results from analyses and simulations of time to incident difficulty of activities of daily living (ADL) in the Cardiovascular Health Study when missing data were imputed simultaneously or sequentially.</p><p><b>RESULTS: </b>Results differed with imputation methods. The largest proportional differences in 12 risk factor parameter estimates were heart failure by 106%, social support by 33%, and arthritis by 27%.</p><p><b>CONCLUSION: </b>Decedents' final characteristics were influential on future imputations of those with missing values.</p>
DOI10.1080/0361073X.2013.741968
Alternate JournalExp Aging Res
PubMed ID23316735
PubMed Central IDPMC3547387
Grant ListN01-HC-80007 / HC / NHLBI NIH HHS / United States
U01 HL080295 / HL / NHLBI NIH HHS / United States
N01 HC015103 / HC / NHLBI NIH HHS / United States
P30AG21342 / AG / NIA NIH HHS / United States
N01HC55222 / HL / NHLBI NIH HHS / United States
N01-HC-85086 / HC / NHLBI NIH HHS / United States
N01HC85086 / HL / NHLBI NIH HHS / United States
P30 AG021342 / AG / NIA NIH HHS / United States
K23AG030986 / AG / NIA NIH HHS / United States
N01 HC-55222 / HC / NHLBI NIH HHS / United States
N01-HC-75150 / HC / NHLBI NIH HHS / United States
N01HC75150 / HL / NHLBI NIH HHS / United States
N01-HC-85079 / HC / NHLBI NIH HHS / United States
K23 AG030986 / AG / NIA NIH HHS / United States
N01HC85079 / HL / NHLBI NIH HHS / United States
N01 HC045133 / HC / NHLBI NIH HHS / United States
N01 HC035129 / HC / NHLBI NIH HHS / United States