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Egg consumption and risk of type 2 diabetes in older adults.
Tuesday,2012-11-06 12:19 America/Los_Angeles — eenright
| Title | Egg consumption and risk of type 2 diabetes in older adults. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Djoussé, L, Kamineni, A, Nelson, TL, Carnethon, M, Mozaffarian, D, Siscovick, D, Mukamal, KJ |
| Journal | Am J Clin Nutr |
| Volume | 92 |
| Issue | 2 |
| Pagination | 422-7 |
| Date Published | 2010 Aug |
| ISSN | 1938-3207 |
| Keywords | Aged, Blood Glucose, Cholesterol, Dietary, Diabetes Mellitus, Type 2, Diet, Diet Surveys, Eggs, Feeding Behavior, Female, Humans, Insulin, Insulin Resistance, Male, Proportional Hazards Models, Prospective Studies, Risk Factors, Surveys and Questionnaires |
| Abstract | <p><b>BACKGROUND: </b>Type 2 diabetes (T2D) remains an important public health issue in the United States. There are limited and inconsistent data on the association between egg consumption and fasting glucose or incident diabetes.</p><p><b>OBJECTIVES: </b>We assessed the association between egg intake and incident diabetes in older adults.</p><p><b>DESIGN: </b>In this prospective study of 3898 men and women from the Cardiovascular Health Study (1989-2007), we assessed egg consumption by using a picture-sorted food questionnaire and ascertained incident T2D annually by using information on hypoglycemic agents and plasma glucose. We used Cox proportional hazards models to estimate adjusted relative risks.</p><p><b>RESULTS: </b>During a mean follow-up of 11.3 y, 313 new cases of T2D occurred. Crude incidence rates of T2D were 7.39, 6.83, 7.00, 6.72, and 12.20 per 1000 person-years in people who reported egg consumption of never, <1 egg/mo, 1-3 eggs/mo, 1-4 eggs/wk, and almost daily, respectively. In multivariable-adjusted models, there was no association between egg consumption and increased risk of T2D in either sex and overall. In a secondary analysis, dietary cholesterol was not associated with incident diabetes (P for trend = 0.47). In addition, egg consumption was not associated with clinically meaningful differences in fasting glucose, fasting insulin, or measures of insulin resistance despite small absolute analytic differences that were significant.</p><p><b>CONCLUSION: </b>In this cohort of older adults with limited egg intake, there was no association between egg consumption or dietary cholesterol and increased risk of incident T2D.</p> |
| DOI | 10.3945/ajcn.2010.29406 |
| Alternate Journal | Am. J. Clin. Nutr. |
| PubMed ID | 20534749 |
| PubMed Central ID | PMC2904037 |
| Grant List | N01 HC-35129 / HC / NHLBI NIH HHS / United States N01-HC-85085 / HC / NHLBI NIH HHS / United States U01 HL080295 / HL / NHLBI NIH HHS / United States N01-HC-85081 / HC / NHLBI NIH HHS / United States 5K01-HL70444 / HL / NHLBI NIH HHS / United States N01-HC-85086 / HC / NHLBI NIH HHS / United States N01-HC-85082 / HC / NHLBI NIH HHS / United States N01 HC-55222 / HC / NHLBI NIH HHS / United States N01-HC-85083 / HC / NHLBI NIH HHS / United States N01-HC-85080 / HC / NHLBI NIH HHS / United States N01 HC-15103 / HC / NHLBI NIH HHS / United States R01 HL094555-01A1 / HL / NHLBI NIH HHS / United States N01-HC-85079 / HC / NHLBI NIH HHS / United States N01-HC-85084 / HC / NHLBI NIH HHS / United States |