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Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group.

TitleUse of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group.
Publication TypeJournal Article
Year of Publication1991
AuthorsO'Leary, DH, Polak, JF, Wolfson, SK, Bond, MG, Bommer, W, Sheth, S, Psaty, BM, Sharrett, AR, Manolio, TA
JournalStroke
Volume22
Issue9
Pagination1155-63
Date Published1991 Sep
ISSN0039-2499
KeywordsAge Factors, Aged, Arteriosclerosis, Carotid Arteries, Carotid Artery Diseases, Carotid Artery, Internal, Female, Humans, Image Interpretation, Computer-Assisted, Image Processing, Computer-Assisted, Male, Prospective Studies, Ultrasonography
Abstract<p>Carotid sonography is being performed on more than 5,000 participants in the Cardiovascular Health Study, a prospective, multicenter study of cardiovascular disease in men and women aged 65 years and older. The sonographic methods used to examine and measure the extracranial carotid arteries are described. Initial validation studies were performed on 61 subjects with a mean age of 68.6 years. Analysis of within- and between-sonographer differences and between-reader differences were performed for selected variables. In general, the mean absolute differences for within- and between-sonographer comparisons were small, with even less variability between readers. Variability was less for the common carotid artery than for the internal carotid artery. These data suggest that carotid sonography is a reliable and reproducible method for use in the study of carotid atherosclerosis in population studies.</p>
DOI10.1161/01.str.22.9.1155
Alternate JournalStroke
PubMed ID1926258
Grant ListN01-HC85079 / HC / NHLBI NIH HHS / United States
N01-HC85080 / HC / NHLBI NIH HHS / United States
N01-HC85081 / HC / NHLBI NIH HHS / United States